Organ transplantations

High risk
  • Candidates and recipients of organ transplantations with severe associated comorbidities
  • Less than 12 months after receiving depletion immunosuppression and combined induction and antirejection regimens
  • Significant clinically manifested immunodeficiency (hypogammaglobulinemia, neutropenia)
  • Bone disease in the stage of treated osteoporosis (bisphosphonate, denosumab)
  • Candidates and patients after heart, lung, or multivisceral transplantation
Medium risk
  • Candidates for organ transplantations without significant associated comorbidities
  • Recipient of organ transplantation within 12 months after surgery without significant associated comorbidities
  • Less than 12 months after antirejection corticosteroid monotherapy
  • Stable recipient more than 12 months after solid organ transplantation with minor to moderate comorbidities as described in the low risk checklist
Low risk
  • Stable recipient more than 12 months after solid organ transplantation
  • Established stable maintenance immunosuppression (corticosteroid dose does not exceed the equivalent of 5 mg prednisone per day)
  • No significant hematopoietic disorders present (especially neutropenia and thrombocytopenia)
  • No significant complications of atherosclerosis (especially advanced ischaemic heart disease) and no significant valvular defects present
  • No significant metabolic complications (especially diabetes and bone disease)